Publications

Search
Preclinical
World ADC San Diego
October 18, 2023
ZW220 – A Potential First-in-Class TOPO1i ADC for the Treatment of NaPi2b-Expressing Solid Tumors​ 
Andrea Hernández Rojas
Preclinical
World ADC San Diego
October 16, 2023
ZW251 – A novel glypican-3 targeting ADC bearing a topoisomerase I inhibitor payload
Laurence Madera
Clinical
AACR-EORTC-NCI
October 13, 2023
Phase 1 Study of Zanidatamab Zovodotin (ZW49): Safety Profile and Recommended Dose (RD) in Patients with Human Epidermal Growth Factor 2 (HER2)-positive Solid Cancers
Preclinical
AACR-EORTC-NCI
October 12, 2023
Refining our understanding of ADCs: Drug development insights from 40 years of data
Raffaele Colombo
Preclinical
Festival of Biologics
October 10, 2023
TOPO1i ADC Platform From Concept to Pipeline Application
Mark Petersen
Preclinical
World Bispecific Summit
October 2, 2023
Engineering Trispecific T-cell Engagers to Address Biological Challenges in the Treatment of Solid Tumors
Nina Weisser
Preclinical
Journal of Medicinal Chemistry
June 12, 2023
Structure–Activity Relationships of Bis-Intercalating Peptides and Their Application as Antibody–Drug Conjugate Payloads
Petersen et al.
Zanidatamab
ASCO
June 2, 2023
Results from the Pivotal Phase 2b HERIZON-BTC-01 Study: Zanidatamab in Previously-treated HER2-amplified Biliary Tract Cancer (BTC)
Pant et al.
Zanidatamab
ASCO
June 4, 2023
Zanidatamab, a HER2-targeted Bispecific Antibody, in Combination With Docetaxel as First-line Therapy for Patients With Advanced HER2-positive Breast Cancer: Updated Results From a Phase 1b/2 Study
Wang et al.
Zanidatamab
Lancet Oncology
June 2, 2023
Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study
Harding et al.
Preclinical
Bioorganic & Medicinal Chemistry Letters
June 2, 2023
Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates
Brant et al.
Preclinical
PEGS
May 15 - May 19, 2023
Optimization of purine-based TLR7 agonists as payloads for immune-stimulating antibody conjugates (ISACs)
Garnett et al.