Breast Cancer

Advanced and/or Metastatic HER2-Positive Breast Cancers

Breast cancer is a type of cancer that occurs when cells of the breast grow uncontrollably. Globally, breast cancer is the most common cancer in women, with 2.3 million women diagnosed each year1.  

Rates are increasing in nearly every region of the world1 with diagnoses rising above a quarter of a million in the US alone1. About 15 to 20 percent of all breast cancers are positive for human epidermal growth factor receptor 2, or HER2, which means they make too much of this protein2. Too much HER2 protein may cause cancer to grow more quickly and spread to other parts of the body3.

Today’s standard treatments for breast cancer include surgery, radiation, chemotherapy, hormone therapy, targeted therapy, and immunotherapy4.

Zymeworks is currently conducting clinical trials to test new potential targeted treatments for this disease.