Collaboration with ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company, to develop an undisclosed number of novel bi-specific antibody oncology therapeutics using Zymeworks' proprietary Azymetric™ platform. Under the terms of the agreement, Zymeworks has granted Lilly and its subsidiaries a worldwide license to the Azymetric™ platform to develop and commercialize therapeutic candidates towards Lilly's therapeutic targets.
Collaboration with Merck to develop bi-specific antibody therapeutics using Zymeworks’ Azymetric™ platform. Under the terms of the agreement Zymeworks has granted Merck, through a subsidiary, a worldwide license to develop and commercialize bi-specific antibodies generated through use of the Azymetric™ platform toward certain exclusive therapeutic targets. Both companies will collaborate to advance the technology platform, with Merck working to progress the bi-specific therapeutic antibody candidates through clinical development and commercialization.
Collaboration to optimize an undisclosed antibody using Zymeworks' ZymeCAD suite of predictive protein engineering tools and XOMA's innovative Targeted Affinity Enhancement (TAE) technology for antibody mutagenesis and optimization.
Collaboration to evaluate the application of Zymeworks' computational biotechnology and predictive protein engineering tools in the context of discovering promising new enzymes for use in DSM’s biocatalytic processes.
Zymeworks and SGI have partnered to make collaborative advancements in high performance scientific computing and research into parallel algorithms for molecular modeling.
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